| Place and date
of birth |
 |
Montevideo, Uruguay, 30th July, 1943. |
| Address |
|
Institute of Cardiovascular Theory, Sotelo 3908, 11700 Montevideo, Uruguay.
|
| Telephone |
|
+ 598-2-3362 341 |
| Fax |
|
+ 598-2-3362 341 |
| University
qualifications (Universidad de la Republica, Montevideo) |
|
Doctor of Medicine (1970) |
|
Certificate of Specialist in Cardiology |
|
Postgraduate Certificate in Biomathematics and Biostatistics |
| Present
positions |
|
Director-General of the Institute of Cardiovascular Theory, Montevideo |
University
positions
(Universidad de la Republica, Montevideo various Faculties, posts and ad interim posts). |
|
Undergraduate Honorary Assistant of Biophysics, 1963 |
|
Undergraduate Honorary Assistant of Physiology, 1963-1965. |
|
Research Fellow, Physiology, 1969-1968. |
|
Instructor of Physiology, 1969-1972. |
|
Lecturer of Physiology Specialized in Cardiovascular and Respiratory Physiology,
1973. |
|
Adjunct Professor of Biochemistry and Biophysics 1975-1983. |
|
Professor of Physiology and Professor -in - Charge of the Institute of
Physiological Sciences, 1975-1977. |
|
Aggregate Professor of Biochemistry and Biophysics, 1983-1985. |
|
Coordinator of Postgraduate Studies in Biomathematics and Biostatistics,
1977-1985. |
| Position in
the Uruguayan Public Health Service |
|
Assistant of Cardiology. |
|
Hospital Maciel, Montevideo, 1967-1975. |
| Positions in the
Fundacion Procardias (Uruguayan Heart Foundation) |
|
Cardiologist, 1970. |
|
Medical Physiologist, 1970-1971. |
|
Director of Centre of Cardiology, 1971-1980. |
|
Director of the Department of Cardiovascular Biophysics and Biomathematics,
1976-1983. |
|
Director of the Department of Cardiovascular Research, 1983-1988. |
| Other
positions |
|
British Council Scholar, Cardiovascular Unit, University of Leeds, U.K.,
1973-1974. |
|
Honorary Clinical Assistant in Cardiology, Leeds General Infirmary, U.K.,
1973-1974. |
| Scientific
societies (membership and executive positions): |
|
Uruguayan Society of Cardiology (Secretary of the Society, 1973). |
|
Uruguayan Society of Pharmacology and Therapeutics. |
|
Inter-American Society of Hypertension (Member of the Long Range Planning
Commitee, 1983-1989). |
|
Inter-American Society for Clinical Pharmacology and Therapeutics: Member of the
Scientific Commitee, 1982-1985;
Chairman of the Scientific Commitee, 1986-1988;
Vicepresident of the Society, 1984-1988;
President-Elect of the Society, 1988-1990;
President of the Society, 1990-1993;
Immediate Past-President of the Society, 1993-1996;
Member of the Junta of Past-Presidente since 1993. |
|
Gesellschaft fur Magnesium-Forschung (F.R.G.). |
|
International Society of Hypertension. |
|
American Society of Heart Failure. |
|
International Society of Cardiovascular Pharmacotherapy. |
|
International Society of Hypertension. |
|
American Society of Hypertension. |
|
Latin American Society of Hypertension (President-Elect, 1993-1996: President,
1996-1999). |
|
International Society of Pathophysiology. |
|
Latin American Society of Heart Failure (President-Elect, 1996-2000). |
| Honorary
membership of scientific societies |
|
Honorary Member of the Southern African Hypertension Society, since 1983. |
|
Honorary Corresponding Member of the Medical Society of the General Hospital of
Mexico City, since 1987. |
|
Honorary Member of the International Society for the Development of Research on
Magnesium, since 1992. |
|
Corresponding Member of the Mexican Society for the Study of Hypertension, since
1993. |
|
Corresponding Member of the Mexican Council Against Hypertension, since 1996.
Honorary Member of the Interamerican Society for Clinical Pharmacology and Therapeutics,
since 1997. |
| Editorial
affiliations |
|
Member of the Editorial Board of Sistole (Uruguayan Archives of Cardiology),
1971-1982. |
|
Editor of Sistole, 1981-1982. |
|
Consulting Editor of the Journal of the American College of Nutrition, 1986-1993. |
|
Member of the International Scientific Council of Atheroma (Portugal), 1987-1991. |
|
Section Editor of Magnesium Research (London-Paris), since 1989. |
|
Member of the Editorial Board of Progress in Pharmacology (Germany), since 1990. |
|
Member of the Editorial Board of Archivos Venezolanos de Farmacologia y
Terapeutica, since 1990. |
|
Member of the Editorial Board of Cardiovascular Drugs and Therapy (USA), since
1990. |
|
Member of the Editorial Board of the Journal of Heart Failure (USA), since 1993. |
|
|
Clinical pharmacology ... diuretics in cardiovascular medicine. |
|
Clinical pharmacology and therapeutic uses of antihypertensive drugs. |
|
Pathophysiology and treatment of heart failure. |
|
Clinical purport of cardiovascular reflexes. |
|
Physiological exercise testing in heart failure. |
|
Clinical scorings for research use in heart failure. |
|
Magnesium turn over in man (physiology, heart failure). |
| University
teaching experience |
|
Carried-out, developed and/or organized pre- and/or post-graduate teaching in the
following disciplines: biomathematics and biostatistics, physiology, biophysics,
biochemistry, etc. |
| Research
achievements |
|
Described the existence of adrenergic-receptor types in the brain, 1967. |
|
Mathematical-modelled the heart rate response to graded Valsalva manoeuvres,
1974. |
|
Developed the FLAMBS (Formal Language Approach to Medical and Biological
Systems), 1966-1993. |
|
Mathematical modelled and remodelled the time course of blood pressure during any
antihypertensive treatment, 1981, 1988. |
|
Mathematical remodelled the time courses of the urinary excretions of fluid and
solutes, and described new variables therefrom (instantaneous renal clearance,
instantaneous fractional excretion, peak flows of urine and urinary solutes), 1987. |
|
Reclassified diuretics completely, from the point of view of their excretory
effects in man, and defined and evaluated diuretic potency in clinical pharmacology in
man, 1986-1993. |
|
Described and defined the mechanisms of the uricosuric action of angiotensin-I
converting enzyme inhibitors and of alpha-1 adrenergic blockers, 1985-1993. |
|
Described the relative independence of the antihypertensive effect of diuretics
with respect to their natriuretic action, 1992. |
|
Advocated the individualized approach to antihypertensive treatment, 1985. |
|
Described the magnesiuretic effect of thiazide-type diuretics in man and
clarified the mechanism of the magnesiuretic action of diuretics, 1984. |
|
Using the FLAMBS, designed various systems which are being tested for their
heuristic value, 1986-1993. |
|
Clarified the mechanism of the beneficial effects of diuretics in chronic
congestive heart failure, 1986-1993., and described new variables to evaluate heart
failure. |
| Books |
|
Reyes AJ, Alcocer L, Velasco M (Eds.): Risks Conveyed by Antihypertensive
Treatment. Gustav Fischer Verlag, Stuttgart New York, 1985. 138 pp. (ISBN 3-437-11036-5;
US ISBN 0-89574-333-5 NY). |
|
Reyes AJ, Leary WP (Eds.): Clinical Pharmacology and Therapeutic Uses of
Diuretics. Gustav Fischer Verlag, Stuttgart New York, 1988. 319 pp. (ISBN 3-437 -11111-6;
US ISBN 0-8974-267-5). |
|
Reyes AJ (Ed.): Diuretics: Clinical Pharmacology and Uses in Cardiovascular
Medicine, Nephrology and Hepatology. Gustav Fischer Verlag, Stuttgart New York, 1992. 674
pp. (ISBN 3-437-11428-x; US ISBN 1-56081-345-8). |
|
Reyes AJ (Ed.): Diuretics in Hypertension and in Heart Failure. Gustav Fischer
Verlag, Stuttgart New York, 1995. 163 pp. (ISBN 3-347-11614-2; US ISBN 1-56081-408-x). |
| Other
publications |
|
Published more than 200 full original research articles and reviews. |
|
|
