MANAGEMENT OF RISK FACTORS FOR CORONARY HEART DISEASE

Foreword Global Risk Assessment Plasma lipids and lipoproteins Family history of coronary disease Hypertension Cigarette smoking Diabetes Obesity Thrombogenic risk factors Age Sex Clinical Assessment of Global Risk of Coronary Heart Disease Informed clinical judgement of a patient's risk for cardiovascular disease Sources of high cardiovascular risk Risk factors for coronary heart disease Lipid Lowering in the Prevention of Coronary Heart Disease Hyperlipidaemia Lipid measurements Treatment of Hyperlipidaemia Management by conservative measures Drug treatment Target Levels for Plasma Cholesterol and LDL Cholesterol Mild risk Moderate risk High risk Management of Hypercholesterolaemia Action limits Conservative measures Drug treatment Retesting Management of Combined (Mixed) Hyperlipidaemia Action limits Conservative measures Drug treatment Retesting Management of Hypertriglyceridaemia Action limits Conservative measures Drug treatment Retesting Management of Hypertension Non-pharmacological treatment Drug treatment Management of Diabetic and Thrombogenic Risk Factors Reducing cardiovascular risk in diabetic patients Reducing thrombogenic risk factors Drug therapy Smoking Cessation Brief individual counselling Extended counselling Nicotine replacement Modifying of enviroment Management of Overweight Treatment of obesity Weight-reducing programme Desirable Body Weight Body Mass Index Lipid-lowering Diet Recommended foods Foods for use in moderation Foods to be avoided Calorie-restricted Lipid-lowering Diet Foods without restriction Foods permitted in controlled quantities Physical Exercise Aerobic exercise The exercise regimen Duration and frequency The need for supervision Lipid-lowering Agents Bile acid sequestrants HMG CoA reductase inhibitors Fibric acid derivatives (fibrates) Nicotinic acid

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