RT-33
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Sensitivity and specificity of
head-up tilt testing with orciprenaline
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Sven Reek, Daniela Polywka,
Helmut U. Klein.
Department of Cardiology, University Hospital Magdeburg, Magdeburg, Germany
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Introduction
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Syncope is a common medical problem and accounts for
about 3% of all emergency room visits and up to 6% of general hospital admissions1,2. Syncope has an extensive differential diagnosis
including organic heart disease, cerebrovascular disease and a variety of psychiatric and
neurologic disorders. The vast majority of patients who experience syncope have no organic
abnormalities3. In these cases neurally mediated
mechanisms are the predominant cause of the syncopal spell4-6.
In patients with recurrent unexplained syncope with no suspected organic heart disease
passive head-up tilt testing is the recommended diagnostic approach7.
The ideal protocol for head-up tilt testing is still a matter of debate. We report our
results with head-up tilt testing with pharmacological provocation in patients with
recurrent syncope and apparently healthy control subjects.
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