Andrea Colella, Giuseppe
Vaccari*, Enrico Dovellini*, Gian Carlo Calamai*, Gianni Plicchi**, Massimo Bonacchi*,
Marino Vaccari*, Antonio Michelucci, Maria Cristina Porciani, Luigi Padeletti, Gian Franco
Gensini.
Dept. of Internal Medicine and Cardiology, University of Florence, Dept. of Cardiology and
Cardiac Surgery, Florence, Dept. of Engineering, University of Bologna, Italy
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Recently a new sensor based on a microaccelerometer
mounted in the tip of a standard ventricular pacing lead has been developed for myocardial
contractility assessment1,2.
At present a new DDDR pacemaker is under clinical evaluation in Europe and 113
chronical implants have been made (as in April 1997).
Peak endocardial accelerometer (PEA) provides a direct measurement of the amplitude of
myocardial vibrations generated during the isovolumic contraction of the heart, and
associated with the first heart sound.
The good correlation between PEA and LV dP/dt max during adrenergic stimulation (r
> 0.9, p < 0.001)3 and the dependence of PEA on
the activity of the left ventricle4 offer potential for
diagnostic applications in myocardial function monitoring. The intrinsic structure of the
sensor, which is sealed into a hermetic and rigid capsule, makes it very suitable for
chronical implants and the fibrosis surrounding the lead increases the mechanical contact
between the tip and heart wall, improving the performance of the sensor.
We investigated the usefulness of PEA integrated into a pacemaker system (PMS)
(BEST-Living, Sorin Biomedica, Italy) for monitoring heart function in patients in
critical setting.
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