RT-94
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Long QT syndrome: clinical,
morphological and clinical features
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Leo A. Bockeria, Elena Z.
Goluchova, Irina P. Poliakova, Eugeni R. Pavlovitch.
Bakoulev Center for Cardiovascular Surgery, Academy of Medical Sciences, Moscow,
Russia
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Introduction and background
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Since 1981 we evaluated more than 200 pts with
malignant ventricular arrhythmias. All of them were operated on1.
Coronary and different noncoronary diseases were the main causes of those arrhythmias.
Long QT syndrome (LQTS) was diagnosed in 30 cases (1.25%). Despite that this disorder is
relatively rare, it is one of the most malignant type of ventricular arrhythmias. Leading
mechanisms have theorethical potential but still poorly defined in clinical practice.
The basis for the development of new diagnostic approach and therapies in that group
of patients was certain contradiction between dramatic course of arrhythmia with high risk
of sudden cardiac death and the existence of multitude of electrophysiological phenomena2,3. The latter occurred during very fertile (as regarding
arrhythmogenesis) zone of ECG thus suggesting the multiple morphological and functional
mechanisms of arrhythmias. Some of those mechanisms should be still understood. Atypical
forms with normal or approximately normal QT on rest ECG are frequently misdiagnosed.
Thus, the diagnosis was difficult since the length and dispersion of the QT interval in
the rest ECG varied and these criteria were not reliable.
The aim of the study was to elaborate some methods providing additional aid in the
identification of pts with LQTS and syncope of unknown origin and to estimate the
underlying electrophysiological features and prospects in surgical treatment.
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