RT-154
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Sotalol efficacy in
supraventricular paroxysmal tachyarrhythmias and ventricular heart rhythm disturbances
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Gulnara Abuladze, Bondo Kobulia,
Merab Mamatsashvili, Zaza Chapichadze, Natalia Gonjilashvili.
Scientific-Research Institute of Clinical and Experimental Cardiology, Tbilisi,
Georgia
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Introduction
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Despite the achievements of the cardiac arrhythmia
treatment, still there are many problems left unsolved, especially in the pathogenesis of
mechanisms of heart rhythm disturbances, which determines differentiated use and efficacy
of various antiarrhythmic drugs.
Recently great interest in the new drug (III class, Vaughan Williams classification)
with significant antiarrhythmic efficacy in various types of heart rhythm disturbances and
minimal side effects arise1-5.
The aim of our investigation was an evaluation of antiarrhythmic efficacy of the III
class drug sotalol with the beta-blocking properties in supraventricular paroxysmal
tachy-arrhythmias and ventricular heart rhythm disturbances.
We study the efficacy of this antiarrhythmic drug taking into consideration the
significance of the clinical electrophysiological and ECG-monitoring data in each
individual case.
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