RT-216
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Role of ICD for the primary
prevention of sudden death in post-myocardial infarction patients
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Antonio Raviele, Aldo Bonso,
Gianni Gasparini, Sakis Themistoclakis, Franco Giada.
Division of Cardiology, Umberto I Hospital, Mestre-Venice, Italy
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Abstract
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This article is a review on the prophylactic use of
ICD in post-myocardial infarction patients. The rationale for this use and the results of
recently terminated randomized trials, as well as the study design and the expectations of
other still ongoing or just starting trials, are discussed. It is clear that, at the
present time, the prophylactic use of ICD is justified only in a very selected and small
subgroup of high-risk patients with previous myocardial infarction, ie those that fit the
MADIT criteria.
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Key Words
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Implantable cardioverter defibrillator -
primary prevention of sudden death
postinfarction patients, prophylatic ICD implantation, MADIT trial, clas I, III drugs,
amiodarone, dl-sotalol, beta-blockers, CABG trial, MUSTT trial, SCD-HeFT trial, MADIT II
trial, BEST ICD trial, left ventricular function, non-sustained ventricular tachycardia,
mortality rate, cost-effectivenes analysis, R
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