S-65
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Antiarrhythmic drug activities
on the vulnerable parameters
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R.W.F. Campbell.
Academic Cardiology Department, Freeman Hospital, Newcastle-upon-Tyne, UK
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Abstract
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The Sicilian Gambit originated the concept of
vulnerable parameters in arrhythmia treatment. Clinical arrhythmias are complex with many
potential vulnerable and modifiable parameters. Antiarrhythmic drugs are similarly
complex. Despite the seeming impossible number of arrhythmia - drug permutation,
consideration of vulnerable parameters is an increasingly attractive management strategy.
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Key Words
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Treatment of arrhythmias – mechanisms
vulnerable parameters, Sicilian Gambit, congenital long QT syndrom, atrial flutter, atrial
fibrillation, multiplicity of factors, ventricular fibrillation, R
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