RT-46

14th International Congress
THE "NEW FRONTIERS"
OF ARRHYTHMIAS 2000

Jan. 29 - Feb. 5, 2000
Marilleva, Trento, Italy

RT-46

Permanent junctional reciprocating tachycardia in infants and children: pharmacological therapy and timing of radiofrequency transcatheter ablation

Fabrizio Drago, Maurizio Bevilacqua, Andrea Mazza*, Massimo Stefano Silvetti, Paolo Versacci, Silvia Anaclerio, Pietro Ragonese.
Bambino Gesu Hospital, Rome, *S. Camillo Hospital, Rome, Italy

Abstract

Fourteen children (6 males, 8 females, mean age 60.7±60.6 months, median 48) affected by permanent junctional reciprocating tachycardia (PJRT) were referred to our Institute between 1987 and 1997. Pharmacological therapy was used in 12 patients: flecainide and propranolol in 5, amiodarone alone in 4 and in association with propranolol in 1, propafenone alone in 1 and in association with sotalol in 1.These drugs were given for a mean period of 62±57.4 months with a complete resolution of the cardiomyopathy in 7/7. Eight patients (mean age 151±16 months) were treated with radiofrequency transcatheter ablation (RFTA) after a mean duration of medical treatment of 101.6±56.46 months. The shortest ventriculo-atrial interval during tachycardia, considered as target for ablation, was recorded in all cases at the coronary sinus ostium (mean value of surface RP’- local VA -40 msec, range -25/-55). Successful ablation of the anomalous pathway was obtained at this site in all patients with an average number of 2.5±1.4 of radiofrequency pulses (mean W 26±3, mean T° 64±5). During the follow-up (mean 23±17 months) 2 patients with a recurrence of PJRT, 1 month and 8 months after the ablation, were submitted to a second successful procedure.
In conclusion, PJRT in pediatric patients can be successfully and safely treated with antiarrhythmic drugs, allowing radiofrequency ablation to be delayed until the children have reached an adequate growth. In our experience the site of successful ablation was always at the ostium of coronary sinus.

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