Carlo Pappone, Salvatore Rosanio, Filippo Gugliotta, Adriano Salvati, Cosimo Dicandia, Gabriele Vicedomini, Vincenzo Santinelli, SimoneGulletta, Patrizio Mazzone,Giuseppe Oreto, Sergio Chierchia.
Division of Cardiology, Hospital S.Raffaele, Milan, Italy
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We selected 9 heparin-treated patients
(7 men, age 29 to 79 years) with drug-refractory permanent AF (duration 5.7±2.2 months),
and no left atrial (LA) thrombi by transesophageal echocardiography (TEE). Six patients had
left ventricular disease: 1 ischemic; 3 hypertensive; and 2 dilated. Procedures were performed
in sinus rhythm achieved by internal electrical cardioversion. RF lesions, deployed transseptally
via a NaviStar catheter (CARTO, Biosense/Webster), consisted of a series of contiguous focal
lesions (guided by CARTO) located around the anatomic orifice of each PV. RF power at each
site was titrated by electrogram amplitude reduction ³75%. Pre- and post-ablation evaluation
included routine 48-hour telemetry monitoring, TEE, monthly and symptomatic Holter monitoring,
and daily symptom diaries.
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