RT-92
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Ibutilide, a new class III antiarrhythmic drug
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Maria Vittoria Pitzalis, Massimo Grimaldi, Paolo Rizzon
Istituto di Cardiologia, Universita di Bari, Italy
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References
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1.
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LEE KS:
Ibutilide, a new compound with potent class III antiarrhythmic activity, activates a slow inward Na current in Guinea pig ventricular cells.
J Pharmacol Exp Ther 1992; 262: 99-108.
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2.
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YANG T, SNYDERS DJ, RODEN DM:
Ibutilide, a methanesulfonamide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (Ikr) in AT-1 cells: concentration-, time-, voltage-, and use-dependent effects.
Circulation 1995; 91: 1799-1806.
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3.
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BASKIN EP, LYNCH JR JJ:
Differential atrial versus ventricular activities of class III potassium channel blockers.
JPET 1998; 285: 135-142..
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4.
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NACCARELLI JV, LEE KS, GIBSON JK, VANDER LUGT J:
Electrophysiology and pharmacology of ibutilide.
Am J Cardiol 1996; 78 (Suppl): 12-16.
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5.
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ANONYMOUS:
Ibutilide.
Med Lett Drugs Ther 1996; 38: 38.
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6.
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JUNGBLUTH GL, VANDERLUGT JK, WELSHMAN IR:
Relationship between subjects age and QTc interval prolongation induced by the class III antiarrhythmic drug ibutilide (abstract).
Clin Pharmacol Ther 1996; 59: 164.
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7.
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STAMBLER BS, BECKMAN KJ, KADISH AH, ET AL:
Acute hemodynamic effects of intravenous ibutilide in patients with or without reduced left ventricular function.
Am J Cardiol 1997; 80: 458-463.
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8.
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ELLENBOGEN KA, STAMBLER BS, WOOD MA, ET AL, FOR THE IBUTILIDE INVESTIGATORS:
Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-response study.
J Am Coll Cardiol 1996; 28: 130-136.
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9.
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STAMBLER BS, WOOD MA, ELLENBOGEN KA, PERRY KT, WAKEFIELD LK, VANDERLUGT JT:
Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation.
Circulation 1996; 94: 1613-1621.
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10.
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STAMBLER BS, WOOD MA, ELLENBOGEN KA:
Antiarrhythmic actions of intravenous ibutilide compared with procainamide during human atrial flutter and fibrillation.
Circulation 1997; 96: 4298-4306.
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11.
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HARRY JD, PERRY KT, GRAUWELS D, WAKEFIELD LK, VANDERLUGT JT:
A multinational study comparing the safety and efficacy of intravenous ibutilide fumarate compared with the safety and efficacy of intravenous dl-sotalol in termination of atrial flutter and atrial fibrillation.
Technical Report on file with FDA.
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12.
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STAMBLER BS, WOOD MA, ELLENBOGEN KA:
Comparative efficacy of intravenous ibutilide versus procainamide for enhancing termination of atrial flutter by atrial overdrive pacing.
Am J Cardiol 1996; 77: 960-966.
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13.
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ORAL B, SOUZA JJ, MICHAUD JF, ET AL:
Facilitating transthoracic cardioversion of atrial fibrillation with ibutilide pretreatment.
N Engl J M ed 1999; 340: 1849-1854.
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