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14th International Congress
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RT-102 |
Dispersion of ventricular repolarisation: reality? illusion? significance? |
Federico Lombardi, Andrea Colombo, Sebastiano Belletti, Alessandro Verzoni, Ezio Calosso, Angelo Beltrami, Cesare Fiorentini
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QT variability |
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Beat to beat changes in QT interval can be measured during a 24 hour Holter recording with appropriate algorithm to adequately detect fluctuations in the ventricular repolarisation process. At the moment the major limitation for a robust appraisal of the dynamic behaviour of QT interval is the difficulty of obtaining an automatic and precise determination of T wave end. This was the main reason for computing QT interval duration on template of averaged cycles with predetermined RR interval duration rather that on a beat to beat basis. With this approach, Coumel and Co-workers showed7 that the difference between QT values measured during day and night time was reduced in patients with coronary artery disease or left ventricular hypertrophy in comparison to normal controls. An alternative approach is the one based on computation of QT peaks (>500 msec), which was found effective to evaluate alteration in the repolarisation process and to identify patients at greater arrhythmic risk after myocardial infarction8. |
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