Roberto Neri, Antonio Silvio Cesario, PieroPalermo, DanielaBaragli, Maria Luisa d’Ettorre, Sergio Cavaglia*, GiancarloGambelli.
Division of Cardiology G.B. Grassi Hospital, Rome, *Medtronic Italia, Rome, Italy
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Simoultaneous right and left ventricular
pacing has recently been introduced for the treatment of patients with severe heart
failure and significant intraventricular and/or atrio-ventricular conduction defects1-3.
The goal of multisite pacing is to correct the electrical and mechanical asynchrony of
the left heart, which is frequently present in dilated cardiomyopathy. Early results of
uncontrolled studies in patients (pts) with refractory heart failure3,4 have shown an
improvement of the NYHA functional class after the implantation of an atrio-biventricular
pacing system.
Preliminary hemodynamic studies, using thoracothomic leads implantation2 have
shown that biventricular pacing increase cardiac index and decrease pulmonary
capillary pressure. These results have been confirmed using endocardial left and
right ventricular pacing5.
The introduction of specifically designed coronary veins leads has made it possible
to achieve left ventricular pacing via the coronary sinus (CS) with good success rate6.
However, due to variations of coronary veins anatomy, the placement of the pacing
electrode into an appropriate CS branch is often difficult. The detailed knowledge
of the anatomy of coronary veins may be helpful in anticipating potential anatomical
obstacles and in selecting the appropriate CS branch. Although the anatomy of
coronary sinus system has already been reported in an unselected patient population7,
detailed informations of coronary veins anatomy in pts with dilated and failing
hearts are lacking. The purpose of this study is to evaluate the angiographic anatomy
of CS vein system in potential candidates to biventricular pacing using balloon
occlusion retrograde venography.
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