Roberto Neri, Antonio Silvio Cesario, PieroPalermo, DanielaBaragli, Maria Luisa d’Ettorre, Sergio Cavaglia*, GiancarloGambelli.
Division of Cardiology G.B. Grassi Hospital, Rome, *Medtronic Italia, Rome, Italy
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BACKGROUND. Atrium-biventricular cardiac
stimulation, using transvenous pacing of the left ventricle (LV) through coronary sinus
(CS) branches, is increasingly recognized as a valuable treatment to improve
hemodynamic and clinical status in selected patients (pts) with severe heart failure.
However, due to variations of coronary veins anatomy, the placement of the pacing
electrode into an appropriate CS branch is often difficult. The purpose of this study is
to evaluate the angiographic anatomy of CS vein system in potential candidates to
biventricular pacing using a balloon occlusion retrograde venography.
METHODS. Balloon occlusion CS venograms were performed in 14 pts (age 65±15 yrs,
11 males, LVEF 22%±7%, QRS 139±2 ms, NYHA class III). Contrast was injected using a
6F balloon tipped catheter (Medtronic Inc., Minneapolis, MN, USA) Digital images were
analyzed by two different observers for description oc:\www diameters of the CS and location,
number, dimension, angulation and tortuosity of CS tributaries.
RESULTS. The average diameters of the proximal, mid and distal CS were the
following: 9.7±2.4 mm; 6.3±1.4 mm; 5.5±0.9 mm. The mid cardiac vein (4.2±2.1 mm)
draining in the CS close to the ostium was identified in 14/14 venograms (100%).
The great cardiac vein (4.6±2.8 mm) draining into the distal CS was imaged in 13/14
(93%). A postero-lateral or a lateral vein (3.3±1.3 mm) draining into the CS or into the
great cardiac vein was imaged in 14/14 (100%) of venograms. Postero-lateral veins
showed an acute angle (<90°) at the junction with the draining vessels in 73% while
lateral veins in 33% of cases.
CONCLUSIONS. In this study, CS tributaries with location and size suitable for the
insertion of a permanent LV pacing lead could be always identified by retrograde
venography. However, anatomical obstacles may prevent adequate lead placement
unless material specifically designed to cross sharp angulations at the branching sites
is available.
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