RT-127
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Ventricular tachycardia in Chagas’ heart disease
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Ivan Mendoza, Federico Moleiro, Juan Marques, Francesca Misticchio, Alvaro Matheus, Freddy Rodríguez, Ivan Mendoza Britto, Julio Guerrero, Agustin Castellanos.
Section of Cardiology,
Tropical Medicine Institute, Central University of Venezuela,
Caracas, Venezuela, Memorial Hospital, University of Miami,
Miami, USA
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Chagas’ heart disease as a problem of public healt
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American trypanosomiasis or chagas’ disease, first described in 1909 by
Carlos Chagas who also discovered its aetiological agent and mode of transmission, is a disabling and potentially
lethal disease1. It is caused by the flagellate parasite trypanosoma cruzi, a protozoan harbores by a variety of domestic
and wild animals1. The insect vectors of the disease are present throughout most South and Central America, and their
zone of distribution extend across the southern United States, where at least some of these vectors are infected with
trypanozoma2,3. Charles Darwin probably contracted the disease during his expedition to South America, as suggested
by his description of the “benchuca” sting and the nature of his late life symptoms4. Although the true prevalence of
Chagas’ heart disease is unknown, these rough estimates indicate that in Latin America, 20 million people are thought
to have Chagas’ disease and 90 million are considered to be at risk of infection2. It is the most common cause of
dilated cardiomyopatly in countries where the disease is endemic5,6.
As a result of modern transportation and inmigration, Chagas’ disease is now a widen problem, especially in United
States and Europe3. The two most important public health questions related the presence of Trypanosoma Cruzi
infected inmigrants in Europa, the United States and Canada are3: 1) the prevention of transmission of Chagas’ disease
via blood transfunsion; 2) the detection and medical care of patients with chronic Chagas’ heart disease.
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