Prapa Kanagaratnam, Vias Markides, Dominic W.Lamb, Richard J.Schilling, D. Wyn Davies, Anthony W.C. Chow, Pravina Patel, Nicholas S. Peters.
St Mary’s Hospital and Imperial College School of Medicine, London, UK
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Although there is extensive literature on cellular electrophysiology and
atrial activation in animal models, there continues to be little information on how cellular electrophysiology in
concert with tissue architecture determines the conduction properties of the human atrium.
Early data from a programme of human studies, incorporating both epicardial and non-contact endocardial
mapping, are providing some insight into the relationship between atrial structure, ultrastructure and conduction
in the normal and arrhythmic human atrium, and have been presented at international meetings in past 12
months.
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