RT-186
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Pacing techniquesfor prevention and termination of atrial fibrillation: analysing mechanisms of efficacy and results of clinical trials
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Sanjeev Saksena.
UMD-Robert Wood Johnson Medical School, New Brunswick & Director, Arrhythmia and Pacemaker Service, Eastern Heart Institute-Atlantic Health Systems, Passaic, USA
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Abstract
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Pacing techniques are being increasingly used for prevention of atrial
fibrillation (AF), and are being considered in devices for termination of this arrhythmia. New concepts of the
mechanisms of efficacy of atrial pacing in prevention of AF include appreciation of direct effects on the
electrophysiologic properties of the atrial substrate, especially with novel pacing methods such as dual site atrial
pacing. Recent clinical studies from cnters worldwide confirm the efficacy of dual site atrial pacing in increasing
the arrhythmia free periods and improving rhythm control in refractory and new onset AF and single site atrial
pacing in prevention of AF in high risk patients such as sick sinus syndrome. Termination of atypical atrial flutter
or organized onset arrhythmias in AF with high frequency pacing is being investigated and pilot clinical trials are
confirming a role for this modality. New devices incorporating these innovative pacing therapies are now being
evaluated for specific device therapy in atrial fibrillation.
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Key Words
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